The essential role of macrophage memory in disease responses
Macrophage memory is closely associated with various diseases. As a novel strategy for diseases prevention and treatment, macrophage memory is beneficial for promoting host immune response against infections. In contrast, this type of memory may be maladaptive or potentially detrimental in the context of transplant rejection or immune-mediated and chronic inflammatory diseases, such as rheumatoid arthritis and atherosclerosis 10, 54, 55.