Figure 2. Body and adipocyte weight of DIO mice treated with CMC, AdipoAI and AdipoRON for 4 weeks (A) Concept strategy of in vivo trial (B) Comparative Body weights measured from 18-21 weeks in DIO mice treated with CMC (0.5%), AdipoAI (25 mg/kg) and AdipoRON (50 mg/kg) (C & D) changes in fat Inguinal and epididymal fat contents for gauging comparative adipose tissue biology in DIO mice models (E) liver weights of DIO mice with respective treated groups recorded at 21 weeks. Data were analyzed by using ordinary 1-way followed by Šidák’s post hoc test. all the values are presented as mean ± SD with three independent experiments sets with *p<0.05; **p<0.01.