AdipoAI administration improved insulin resistance and glucose
tolerance in DIO mice models
The DIO mouse models were subjected to glucose and insulin tolerance
test in accordance with our perceived plan of interventional strategy
for developing T2D pathology (Fig 2A, B). OGTT showed time dependent
decrease in serum glucose profile for AdipoAI and AdipoRON groups when
compared to those of CMC (Carboxymethylcellulose) groups (Fig 2A).
Further, insulin tolerance test resulted in gradual reduction in the
levels of serum glucose in AdipoAI and AdipoRON groups when compared to
that of CMC group suggesting that AdipoAI have comparable beneficial
features as that of AdipoRON (Fig 2B).