Variable
|
GFR <60 N = 339 | GFR ≥60 N = 317 |
p value
|
Age (years)* | 73.6 ± 13.3 | 67.1 ± 15.4 | <0.001 |
Gender | 0.015 | ||
Men | 154 (45%) | 174 (55%) | |
Women | 185 (55%) | 143 (45%) | |
African-American | 271 (80%) | 258 (81%) | 0.639 |
Latino | 61 (18%) | 51 (16%) | 0.517 |
BMI (kg/m2)+ | 27.5 (9.5) | 27.6 (9.1) | 0.433 |
Hypertension | 315 (93%) | 255 (80%) | <0.001 |
Dyslipidemia | 136 (40%) | 117 (37%) | 0.383 |
Smoking | 116 (35%) | 145 (46%) | 0.003 |
DM | 134 (40%) | 85 (27%) | <0.001 |
CAD | 80 (24%) | 56 (18%) | 0.067 |
PVD | 34 (10%) | 27 (9%) | 0.506 |
CHF | 113 (34%) | 90 (29%) | 0.198 |
Prior stroke | 77 (23%) | 54 (17%) | 0.076 |
CHADVasc2 | <0.001 | ||
0 | 5 (1%) | 22 (7%) | |
1 | 18 (5%) | 41 (13%) | |
>1 | 316 (93%) | 254 (80%) | |
Oral Hypogly | 65 (19%) | 43 (14%) | 0.053 |
Insulin | 46 (14%) | 13 (4%) | <0.001 |
Aspirin | 140 (41%) | 129 (41%) | 0.850 |
Plavix | 24 (7%) | 15 (5%) | 0.204 |
Statins | 124 (37%) | 112 (35%) | 0.739 |
Β-Blockers | 155 (46%) | 136 (43%) | 0.447 |
ACEI/ARB | 146 (43%) | 144 (45%) | 0.543 |
Coumadin/AC | 133 (39%) | 135 (43%) | 0.383 |
% Time on AC+ | 62.7 (43.0) | 60.4 (33.0) | 0.551 |
Digoxin | 42 (12%) | 37 (12%) | 0.778 |
Amiodarone | 8 (2%) | 3 (1%) | 0.159 |
BiDil | 20 (6%) | 7 (2%) | 0.017 |
CCB-DH | 82 (24%) | 64 (20%) | 0.218 |
CCB-NonDH | 45 (13%) | 25 (8%) | 0.026 |
Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise | Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise | Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise | Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise |