Table 3- Cox Proportional Hazard Regression Analysis for the Time to the Development of Myocardial Infarction, Stroke, Death, or any of these events among patients with GFR <60 vs. patients with GFR ≥60
Outcome Prognostic Factor Hazard Ratio (95% CI) P-value*
Myocardial infarction GFR <60 1.88 (1.17, 3.04) 0.009
CAD 2.79 (1.78, 4.39) <0.001
Stroke GFR <60 1.13 (0.77, 1.65) 0.529
Age (per 10 years) 1.31 (1.13, 1.51) <0.001
Prior stroke 1.99 (1.36, 2.92) <0.001
Death GFR <60 1.63 (1.11, 2.41) 0.014
Age (per 10 years) 1.43 (1.23, 1.66) <0.001
Oral hypoglycemics 1.77 (1.15, 2.72) 0.009
Insulin 0.33 (0.13, 0.82) 0.017
Myocardial infarction 2.24 (1.46, 3.43) <0.001
Any event GFR <60 1.37 (1.05, 1.78) 0.018
Age (per 1 year) 1.32 (1.20, 1.46) <0.001
Prior stroke 1.47 (1.11, 1.94) 0.007
Cox proportional hazards regression model * Cox proportional hazards regression model * Cox proportional hazards regression model * Cox proportional hazards regression model
Abbreviations: GFR: Glomerular filtration rate; CAD: Coronary artery disease Abbreviations: GFR: Glomerular filtration rate; CAD: Coronary artery disease Abbreviations: GFR: Glomerular filtration rate; CAD: Coronary artery disease Abbreviations: GFR: Glomerular filtration rate; CAD: Coronary artery disease